This is unusual.
What you could check:
Do you maintain your stylesheets with the NJX Stylesheet Editor? Remember that they need to be regenerated when upgrading to a new NJX version. In Natural ONE geration is done automatically for you as long as you use the recommended folders.
Do you use proprietary style settings in your stylesheet?
In NJX 8.4.1 the *.js files are refreshed automatically. But the *.css files are not versioned. Did you clear the browser cache?
Do you have custom controls with own java script/html?
I am curious: Would you like to attach one of your layouts, which is broken in Edge/Chrome?