SAP Adapter - Connect to SAP gateway failed : HELP

Has anyone seen this error when sending an IDOCs from SAP to webMethods through the SAP Adpater Listern.

000002 SAPTRP0005E Error in ALE:InboundProcess: Connect to SAP gateway failed
Connect_PM GWHOST=192.168.146.53, GWSERV=sapgw00, ASHOST=192.168.146.53, SYSNR=00

LOCATION CPIC (TCP/IP) on local host
ERROR max no of 100 conversations exceeded

TIME Wed Jul 10 14:30:37 2002
RELEASE 46D
COMPONENT CPIC (TCP/IP)
VERSION 3
RC 466
MODULE r3cpic.c
LINE 10149
COUNTER 18
000003 SAPFUN0008E Error in inbound call for IDOC_INBOUND_ASYNCHRONOUS from QDF_300: com.wm.pkg.sap.BCException: Connect to SAP gateway failed
Connect_PM GWHOST=192.168.146.53, GWSERV=sapgw00, ASHOST=192.168.146.53, SYSNR=00

LOCATION CPIC (TCP/IP) on local host
ERROR max no of 100 conversations exceeded

TIME Wed Jul 10 14:30:37 2002
RELEASE 46D
COMPONENT CPIC (TCP/IP)
VERSION 3
RC 466
MODULE r3cpic.c
LINE 10149
COUNTER 18
000004 SAPLIS0004E Error in SAP Listener: com.sap.mw.jco.JCO$Exception: (104) RFC_ERROR_SYSTEM_FAILURE: See RFC trace file or SAP system log for more details

Hi did you manage to overcome this error. I am trying to post IDOC to SAP systems and I am getting the exact error message.
Any hekp is appreciated.

Thanks,
Madhu