Using Synchronous RFC with 4.6 SAP Adapter

We are upgrading from Enterprise version 5 to IS 6.5. In the Enterprise version we were using SAP Adapter 4.2, but in the new environment we are using SAP Adapter 4.6. We have several cases where we are trying to get data from external systems using RFCs that get kicked off from SAP. In the Enterprise version the information from the RFC gets sent out of SAP, evaluated in the external system and then an RfcProcessOutboundReply is used to send the collected information back into SAP as the result for the original RFC.

We have not been able to duplicate our process from the Enterprise version to the new IS version. Has anyone else run across this issue? If you have any hints or advice would be greatly appreciated. Thanks!