TN Server Error

Hello Friends,

I get prob when i started TN
Plz help me

In webmethod 6.5

TRNSERV.000012.000114 Could not get profile summary (username=Administrator). java.lang.IllegalStateException The main connection to the datastore has not been initialized. Check the Trading Networks JDBC connection pool.

Check that the server is running and accessible. Check that the current user has ACLs to access