System Management Hub very slow (4.4.1)

hello all,

i experience the following problem :
the System Management Hub is very slow. I can still access little databases after a long time (the time to unfold every folder) but i have one big database that i can ot access anymore (i lose the session). Is there something i can do ?

My config is : tamino 4.4.1 (but not the Patch INS44106 suspected to cause schema defining problem, not verified) running on SUSE LINUX 9.2

thanks in advance
thomas

ps : i was working with tamino 4.2.1 until now and never had this problem