I am also facing the same issue.
I have checked config file it looks good and also tools.jar present in the IS location.(IntegrationServer\lib\jars\tools.jar),
I am trying to access a jsp file (http://machine-ip:5555/web/JSPImpl/first.jsp), it shows Apache Tomcat/4.0.2 - HTTP Status 500 - No Context configured to process this request…
still wondering what would be the problem?