WebMethods 6.1 compatibility with iSeries OS/V6R1

Hello,
We are in the process of analyzing a possible upgrade of the IBM iSeries Operating system to Version 6 Release1 (V6R1). In this analysis we need to determine if all out third-party applications interacting with the iSeries will work just fine or will need fixes with V6R1.
My analysis is specific to WebMethods. For reasons I don’t want to explain, we are still using this version of WebMethods 6.1 SP2.
We are trying to determine if we can get by upgrading OS in iSeries without upgrading Webmethods 6.1 due to some restrictions on a third party application using WebMethods.
Does any of you are on WebMethods 6.1 and iSeries Operating system V6R1?

Regards,
M Camejo