Different browser behaving differently while publishing a Shell in MWS


i have created a shell in CAf where we have a left navigation pannel and a right navigation pannel.
When i checked in internetexplorere there is huge space in between right nad left navigation pannel.
But when i chceked the same in Mozila browser its showing fine.The page looks good.space between left nav,right nav,headerand footer is ok.
So different browser are behaving differently.
Can any one please suggest how to fix the issue.